Ephesians 5:17-18

 

 

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Ephesians 5:17 So * then * do not be foolish, but understand what the will of the Lord is. (NASB: Lockman)

Greek: dia touto me ginesthe (2PPMM) aphrones, alla suniete (2PPAM) ti to thelema tou kuriou.
Amplified: Therefore do not be vague and thoughtless and foolish, but understanding and firmly grasping what the will of the Lord is.  (Amplified Bible - Lockman)
NLT:  Don't act thoughtlessly, but try to understand what the Lord wants you to do.  (NLT - Tyndale House)
Phillips:  Don't be vague but firmly grasp what you know to be the will of God. (
Phillips: Touchstone)
Wuest: On this account stop becoming those who are without reflection or intelligence, but be understanding what the will of the Lord is.  (
Erdmans
Young's Literal:  because of this become not fools, but--understanding what is the will of the Lord,

REFERENCES

Albert Barnes
Wayne Barber
Wayne Barber
Wayne Barber
J M Boice
John Calvin
Thomas Constable
Bob Deffinbaugh
Explore the Bible
David Guzik
S Lewis Johnson
John MacArthur
John MacArthur
John MacArthur
John MacArthur
John MacArthur
John MacArthur
John MacArthur
F B Meyer
John Piper
John Piper
John Piper
Ray Pritchard
A T Robertson
Ray Stedman
Marvin Vincent
Precept Ministries

Ephesians 5
Ephesians 5:15-17 Walking as Light in a World of Darkness
Ephesians 5:18: Be Filled With the Spirit - 1

Ephesians 5:18-21: Be Filled With the Spirit - 2
Ephesians 5 Body Life (Audio)

Ephesians 5
Ephesians Expository Notes

Ephesians 5:15-21 Walking Wisely

Ephesians 5:1-21: Imitate God
Ephesians 5
Ephesians 5:3-21 Purity in the Christian Life (Audio)
Ephesians 5:18: Be Not Drunk with Wine - 1

Ephesians 5:18: Be Not Drunk with Wine - 2

Ephesians 5:18: Be Not Drunk with Wine - 3
Ephesians 5:18: Be Filled with the Spirit - 1

Ephesians 5:18-19: Be Filled with the Spirit - 2

Ephesians 5:19: Be Filled with the Spirit - 3

Ephesians 5:18-22: God's Plan For Your Family vs World

Ephesians 5:18 The Message of Pentecost
Ephesians 5:15-20 Urgency And Gratitude 

Ephesians 5:17-20 Singing & Making Melody to Lord

Ephesians 5:18 Be Filled with the Spirit 

Ephesians 5:18: Filled with the Holy Spirit? 

Ephesians 5
Ephesians 5:15-20: Watch How You Walk

Ephesians 5
Ephesians Lesson 1 - 37 pages PDF

SO THEN DO NOT BE FOOLISH: dia touto me ginesthe (2PPMM) aphrones.: (15; Colossians 4:5)

So then - If we are going to maximize the use of the time (opportunities) God's gives us each day, Paul says first stop being foolish or showing lack of sense (the negative). Then he emphasizes (the positive) that we are to discern the will of God day by day. In the next verse Paul explains one of the most important truths about the will of God, negatively not to be drunk with wine but positively to be "drunk" with the Spirit, letting Him control your life.

So then (1223) (dia) in this case is used in its causal sense - in consequence of, by, on the basis of, on account of the evil nature of the days, stop being foolish.

(Not) Be (1096) (ginomai) means to become. The present imperative with a negative commands them to stop an action already in progress - stop becoming foolish. Paul is saying stop acting as if you don’t have the ability to understand the situations that occur in your life and how God wants you to respond because you do have that ability now in Christ, in the New Self. Second Timothy tells us we are not like people who are lost but have minds that have been saved (see word study sophronismos). We can understand what God wants us to do.

Wuest translates it...

On this account stop becoming those who are without reflection or intelligence (Wuest)

Foolish (878)(aphron from a = without + + phren = understanding,  means originally meant diaphragm and was regarded as the seat of mental and spiritual activity, then mind or understanding) is literally a lack of sense, reflection, understanding or reason. Aphron describes one who is not employing his understanding especially as it relates to practical matters. Lack of good judgment. It refers to folly in action. It can express a reckless and inconsiderate habit of one's mind. Not using common sense. Acting rashly. Unwise, inconsiderate. Mindless or unmindful of the consequence of a thought or action.

The aphron was not a dim-witted person or clown (as in ‘play the fool’), but describes the person in Greco-Roman society who had lost the correct measure of himself and the world around him.

Lacking prudence (which is  the ability to govern and discipline oneself by the use of reason and includes the idea of acting with or showing care and thought for the future)

In the present verse a foolish describes one who does not know the will of the Lord. Only as one understands what pleases God can he carry it out in his life, and not to do otherwise is foolish! In Ephesians 5:15  Paul describes the unwise, those who simply lack wisdom, but in this verse, the foolish behave contrary to what they know to be right.

In the OT exalting human reason is folly (aphron). The aphron is the fool who denies God in the Psalms. In Proverbs aphron refers to the simple or inexperienced person. Josephus uses aphron to describe youthful folly or lack of restraint.

Vincent writes that aphron means...

Senseless. In Xenophon’s “Memorabilia,” Socrates, addressing Aristodemus, says, “Which do you take to be the more worthy of admiration, those who make images without sense (aphrona) or motion, or those who make intelligent and active creations?” (1, 4:4). Sometimes, (aphron is used) also, in the sense of crazed, frantic, but never in New Testament. (Vincent, M. R. . Word Studies in the New Testament 1:369)

NIDNTT writes that in classic Greek use...

aphron, senseless, foolish and aphrosune, lack of sense, foolishness (both words from Homer onwards) indicate by the use of the Alpha-privative that the term is essentially defined by a lack or a negation, i.e. lack of insight and reason. But the possible development of a diseased mind is not excluded here either (Homer, Od. 23, 10-14). aphron can thus mean infatuated (Homer, Od. 21, 102) and aphrosune can be referred back to mania (Aristotle, Eth. Nic. 7, 6, both times, incidentally, through active intervention of the gods). But the words chiefly describe deficient perception of value and truth. (Brown, Colin, Editor. New International Dictionary of NT Theology. 1986. Zondervan)

Aphron is used 11 times in the NT (see below) and 111 times in the Septuagint (LXX) (2 Sam. 13:13; Job 2:10; 5:2f; 30:8; 34:36; Ps. 14:1; 39:8; 49:10; 53:1; 74:18, 22; 92:6; 94:8; Prov. 1:22; 6:12; 7:7; 9:4, 13, 16; 10:1, 4, 18, 21, 23; 11:29; 12:1, 15f, 23; 13:16, 20; 14:1, 3, 7f, 16, 18, 24, 29, 33; 15:2, 5, 7, 20; 16:22, 27; 17:2, 7, 10, 12, 16, 18, 21, 24f; 18:6f, 22; 19:10, 13, 25, 28f; 20:3; 21:20; 22:3; 23:9; 24:9, 30; 26:1, 4ff; 27:3, 12, 22; 28:26; 29:11, 20; 30:2, 22; Eccl. 2:14ff, 19; 4:5, 13; 5:1, 3f; 6:8; 7:4ff, 9; 10:2f, 6, 12, 14f; Isa. 59:7; Jer. 4:22; 17:11)

Luke 11:40 "You foolish ones, did not He who made the outside make the inside also? (Comment: Jesus uses aphron to describe the Pharisees because they thought that their  external works based righteousness could gain favor with God.) Jesus called the Pharisees fools for their preoccupation with externals

Luke 12:20 "But God said to him, 'You fool! This very night your soul is required of you; and now who will own what you have prepared?' (Comment: The rich man was a fool because he had failed to prepare to meet God. A fool is the one whose plans end at the grave! In both this verse and the preceding, Luke 11:40, willful and culpable ignorance is involved warranting a strong reproach. The Pharisees and the farmer both refused to take into account what God had revealed to his OT people.)

Romans 2:20 a corrector of the foolish, a teacher of the immature, having in the Law the embodiment of knowledge and of the truth, (Comment: In this context aphron is used by those who are "religious" to refer to those they classify as immature in moral and religious matters.)

1 Corinthians 15:36 You fool! That which you sow does not come to life unless it dies;

2 Corinthians 11:16 Again I say, let no one think me foolish; but if you do, receive me even as foolish, that I also may boast a little.

2 Corinthians 11:19 For you, being so wise, bear with the foolish gladly.

2 Corinthians 12:6 For if I do wish to boast I shall not be foolish, for I shall be speaking the truth; but I refrain from this, so that no one may credit me with more than he sees in me or hears from me.

2 Corinthians 12:11 I have become foolish; you yourselves compelled me. Actually I should have been commended by you, for in no respect was I inferior to the most eminent apostles, even though I am a nobody.

Ephesians 5:17 So then do not be foolish, but understand what the will of the Lord is.

1 Peter 2:15 (note) For such is the will of God that by doing right you may silence the ignorance of foolish men. (Comment: Here foolish describes those obstinately set against the gospel.)

BUT UNDERSTAND WHAT THE WILL OF THE LORD IS: alla suniete (2PPAM) ti to thelema tou kuriou.: (Deuteronomy 4:6; 1 Kings 3:9-12; Job 28:28; Psalms 111:10; 119:27; Proverbs 2:5; 14:8; 23:23; Jeremiah 4:22; John 7:17; Romans 12:2; Colossians 1:9; 1 Thessalonians 4:1-3; 5:18; 1 Peter 4:2)

In Paul presented this same idea earlier when he wrote that believers walking as children of light should continually be

"trying to learn what is pleasing to the Lord." (See note Ephesians 5:10)

Understand (4920) (suniemi from sun = with + hiemi = send) (Click word study of related noun sunesis) literally means to send together or bring together. The idea is to put together "pieces of the puzzle" (so to speak) and to exhibit quick comprehension.  Suniemi is describes the  ability to understand concepts and see relationships between them. Suniemi speaks of reflective thinking. The present imperative indicates this is a command to make this our continual practice.

Suniemi describes the comprehending activity of the mind denoted by suniemi entails the assembling of individual facts into an organized whole, as collecting the pieces of a puzzle and putting them together. The mind grasps concepts and sees the proper relationship between them. Such understanding includes the moral and religious awareness of man’s heart

Will (2307)(thelema from thélo = to will) means what one wishes or has determined shall be done or that which is desired or wished for. It refers to a desire which proceeds from one’s heart or emotions. This term expresses the result of one’s purpose or desire. Thelema has both an objective meaning (“what one wishes to happen”) and a subjective connotation (“the act of willing or desiring”). The word conveys the idea of desire, even a heart’s desire, for the word primarily expresses emotion instead of volition. Thus God’s will is not so much God’s intention, as it is His heart’s desire. It is His will not as a demand but as an inclination of pleasure towards that which is liked, which pleases and creates joy.

Understanding the will of the Lord, is virtually identical to Paul's earlier charge for believers to walk "trying to learn what is pleasing to the Lord' (See note Ephesians 5:10) The subsequent verses explain God's will includes believers being filled with His Spirit, being thankful, submitting to one another, being loving husbands, being obedient children, being disciplining fathers, being obedient slaves and being non-threatening masters. The point is that God's will is best discerned from God's Word.

John explains the basic principle that "obedience is the organ of spiritual knowledge" writing that...

"If any man is willing to do His will, he shall know of the teaching, whether it is of God, or whether I speak from Myself. (John 7:17)

In Romans Paul explains one of the major ways to discern God's will writing...

And do not be conformed (present imperative with a negative means stop an action already in progress) to this world, but be transformed present imperative = be continually transformed = proceeding from and being truly representative of one’s inward character and nature) by the renewing of your mind, that you may prove (see word study on dokimazo) what the will of God is, that which is good and acceptable and perfect. (See note Romans 12:2) (As we choose to be less and less poured into the mold of this world system which is opposed to God and allow God to change us from glory to glory as we take in and live out His sanctifying Word of truth, we are more and more enabled to put things to the test for the purpose of showing them to truly be God's will.)

We can pray for God's will to fill us as Paul prayed for the Colossians writing...

For this reason also, since the day we heard of it, we have not ceased to pray for you and to ask that you may be filled (controlled by - the verb is pleroo, just as in Ephesians 5:18 "be filled with the Spirit") with the knowledge (not an mystical inner impression or feeling but a deep and thorough knowledge of the will of God) of His will in all spiritual wisdom and understanding (See note Colossians 1:9) (Comment: Note that being filled with the knowledge of God's will results in the life or "walk" described in the following verses - we will be enabled to walk  - see notes Colossians 1:10;  1:11; 1:12)

Paul explains that a thankful attitude is God's will for believers writing that...

in everything give thanks; (present imperative) for this is God's will for you in Christ Jesus (NLT writes "No matter what happens, always be thankful, for this is God's will for you who belong to Christ Jesus") (1Thes 5:18) (Comment: Notice that Paul does not say  give thanks for everything but in everything. And in the context of this Ephesians 5, we see that the way in which a believer can have a grateful attitude is by being continually filled with the Holy Spirit - cf notes Ephesians 5:20 "always giving thanks for all things")

MacDonald warns that doing God's will is crucial...

Because of the abounding evil and the shortness of the time, we might be tempted to spend our days in frantic and feverish activity of our own choosing. But this would amount to nothing but wasted energy. The important thing is to find out God’s will for us each day and do it. This is the only way to be efficient and effective. It is all too possible to carry on Christian work according to our own ideas and in our own strength, and be completely out of the will of the Lord. The path of wisdom is to discern God’s will for our individual lives, then to obey it to the hilt. (MacDonald, W & Farstad, A. Believer's Bible Commentary: Thomas Nelson)

Lord (2962) (kurios) signifies sovereign power and absolute authority. He is the One Who has absolute ownership and uncontested power and therefore the One Whose will is good and acceptable and perfect. As His loyal, loving subjects we do well to obey His will.

Wayne Barber sums on this section on knowing the will of the Lord stating that...

Generically, the will of the Lord is that we be strengthened in the inner man by the Spirit of God, that we obey Him, that we depend completely on Him, that we be surrendered in our attitude towards Him. Specifically because of that fear of God, God will give us wisdom in the specific areas of our life.

GEORGE MUELLER
ON FINDING THE WILL OF GOD

1. Surrender your own will.

I seek at the beginning to get my heart into such a state that it has no will of its own in regard to a given matter. Nine-tenths of the trouble with people generally is just here. Nine-tenths of the difficulties are overcome when our hearts are ready to do the Lord's will, whatever it may be. When one is truly in this state it is usually but a little way to the knowledge of what His will is.

2. Do not depend on feelings.

Having done this, I do not leave the result to feeling or simple impression. If so, I make myself liable to great elusions.

3. Seek, the Spirit's will through God's Word.

I seek the will of the Spirit of God through, or in connection with, the Word of God. The Spirit and the Word must be combined. If I look to the Spirit alone without the Word, I lay myself open to great delusion also. If the Holy Ghost guides us at all, He will do it according to the Scriptures and never contrary to them.

4. Note providential circumstances.

Next I take into account providential circumstances. These often plainly indicate God's will in connection with His Word and Spirit.

5. Pray.

I ask God in prayer to reveal His will to me aright.

6. Wait.

The best way to study a subject often begins with a definition of that subject. What do we mean by the will of God? It is that holy and stated purpose of the Father to make His dear children as much like Christ as possible. Without doubt the most important factor in finding God’s will is the Bible itself. God speaks to us not in some loud voice, but through the Scriptures.

1) The Scriptures declare He does have a definite will for my life. “The steps of a good man are ordered by the Lord” (Ps 37:23). “I will instruct you and teach you in the way you should go” (Ps 32:8). See also Eph 2:10; Heb 12:1.

2) God desires us to know this will for our lives. “Therefore do not be unwise, but understand what the will of the Lord is” (Ep 5:17).

3) This will is continuous. It does not begin when I am thirty years of age. God has a will for children, young people, adults, and senior citizens. See Isa 58:11.

4) God’s will is specific. “Your ears shall hear a word behind you, saying, ‘This is the way, walk in it’” (Isa 30:21). “But the way of the upright is a highway” (Pr 15:19).

5) God’s will is profitable (Jos 1:8; Ps 1:1–3).

What is the will of God for us? As we have already noted, it differs from believer to believer. But here are four aspects in the will of God which apply to every Christian:

It is His will that we learn more about God Col 1:9

It is His will that we grow in grace 1Th 4:3

It is His will that we study His Word 2Ti 3:14-17

It is His will that we share our faith  Acts 1:8; 1Ti 2:4 2Peter 3:9

F B Meyer (in his devotional on Mt 6:10) writes that...

MANY PEOPLE shrink from God's will. They think that it always means pain, or sorrow, or bereavement. They always feel melancholy when you speak of doing the Will of God. Alas! how the devil has libeled God. The will of God is the will of a Father. It is the Fatherhood of God going out in action. "It is not the will of your Father that one of these little ones should perish." "This is the will of God, even your sanctification."

If only the will of God were done on earth, as it is done in heaven, there would be peace between the nations, and love and happiness in all our homes. Love would cement the union of all men in a city of blessedness. The fact of the world's present condition is no argument against the beneficence and blessedness of the will of God. It is because men will not do the will of God that things are as they are!

In our own life we shall never be really fight or happy until we have got to the point of saying: "I delight to do Thy will, O my God." We may not begin there. The first step is to choose it, then we shall come to accept it lovingly and thankfully; but, finally, we shall rejoice and delight in it. If you cannot say "Thy Wilt be done," say: "I am willing to be made willing that Thy Will should be done." If your will is like a bit of rough and rugged iron, tell God that you are willing for it to be plunged into the furnace of His love, so that all which is unyielding and obdurate may pass away before the ardent heat of the Divine Fire. Depend on it that He will not fail, nor be discouraged with the long process that may be required; and that He will not be rough or violent. He will stay His east wind. He will keep His hand on the pulse, that He may be aware of the least symptom that the ordeal is too strong.

At first there may be a twinge of pain, as when a dislocated limb is pressed back into its proper position, but afterwards there is the blessed restoration of healthy vigor. You will only lose what you would gladly give up if you know as much as God does of what promotes soul-health. "Whosoever," said our Lord, "will do the Will of my Father, the same is my brother, and sister, and mother." "In His Will is our peace."

PRAYER - Most Gracious God, to know and love whose will is righteousness, enlighten our souls with the brightness of Thy presence, that we may both know Thy Will and be enabled to perform it. AMEN.

The great Puritan writer Thomas Watson listed the following principles to invoke in order to rightly discern God's will...

How shall we do God’s will aright?

(1) Get sound knowledge. We must know his will before we can do it; knowledge is the eye to direct the foot of obedience. The Papists make ignorance the mother of devotion; but Christ makes ignorance the mother of error. ‘Ye do err, not knowing the Scriptures.’ Mt. 22:29. We must know God’s will before we can do it aright. Affection without knowledge, is like a horse full of mettle, but his eyes are out.

(2) If we would do God’s will aright, let us labor for self denial. Unless we deny our own will, we shall never do God’s will. His will and ours are like the wind and tide when they are contrary. He wills one thing, we will another; he calls us to be crucified to the world, by nature we love the world; he calls us to forgive our enemies, by nature we bear malice in our hearts. His will and ours are contrary, and till we can cross our own will, we shall never fulfil his.

(3) Let us get humble hearts. Pride is the spring of disobedience. ‘Who is the Lord, that I should obey his voice?’ Ex. 5:2. A proud man thinks it below him to stoop to God’s will. Be humble. The humble son says, Lord what will you have me to do?’ He puts, as it were, a blank paper into God hand; and bids him write what he will, and he will subscribe to it.

(4) Beg grace and strength of God to do his will. ‘Teach me to do thy will:’ as if David had said, Lord, I need not be taught to do my own will, I can do it fast enough, but teach me to do thy will. Psalm 143:10. And that which may add wings to prayer, is God’s gracious promise, ‘I will put my Spirit within you, and cause you to walk in my statutes.’ Eze. 36:27. If the lodestone draw the iron, it is not hard for the iron to move: if God’s Spirit enable, it will not be hard, but rather delightful to do God’s will.

Martin Luther said...

“If it were in the will of God, I’d plant an oak tree today, even if Christ were coming tomorrow”

When David Livingstone was asked if he didn’t fear that going into Africa was too difficult and too dangerous, he answered,

“I am immortal until the will of God for me is accomplished.”

An illustration of the principles to utilize when seeking the will of God...

F. B. Meyer was sailing many years ago to England from northern Ireland. He told the story of how it was night and, as the ship entered the harbor, nothing was to be seen but a confusing array of lights. Dr. Meyer wondered how the captain could hope to navigate into the harbor safely at night in such a confusing jumble of lights, and so he asked him. The captain took him up to the bridge and said, “You see, sir, it’s really very simple. I’ll show you how. Do you see that big light over to the left? And do you see that other big light over there to the right of it? And now, do you see that outstanding light farther still this way? Well now, keep your eyes on those three lights and see what happens.” As Dr. Meyer watched, the big outer light on the left gradually moved in until it coincided with the middle one. Then, as the ship turned, the light gradually merged into the third. “There now,” said the captain, “all I have to do is to see that those three big lights become one; then I go straight forward.” The point is that the believer also has three lights to guide him into the will of God. When Scripture and conscience are lined up with outward circumstances so that the three become one, we need have no fear. We may go straight ahead. God’s will is clear.

An illustration of how not to discern the will of God...

A middle-aged farmer who had been desiring for years to be an evangelist was out working in the field one day when he decided to rest under a tree. As he looked into the sky he saw that the clouds seemed to form into the letters P and C. Immediately he hopped up, sold his farm, and went out to P-reach C-hrist, which he felt was God’s leading. Unfortunately, he was a horrible preacher. After one of his sermons a neighbor came forward and whispered in his ear, “Are you sure God wasn’t just trying to tell you to P-lant C-orn.”

Related Resources
The "Will of God"

Matthew 6:9-10: Thy Will Be Done - Sermon on Mount On Site

Romans 11:33-12:2: Discovering Will of God by Ray Stedman
What Is the Will of God and How Do We Know It? by John Piper
Experiencing God: Knowing and Doing the Will of God

 

Ephesians 5:18 And do not get drunk with wine, for that is dissipation, but be filled with the Spirit, (NASB: Lockman)

Greek: kai me methuskesthe (2PPPM) oino, en o estin (3SPAI) asotia, alla plerousthe (2PPPM) en pneumati,
Amplified: And do not get drunk with wine, for that is debauchery; but ever be filled and stimulated with the [Holy] Spirit.  (Amplified Bible - Lockman)
NLT: Don't be drunk with wine, because that will ruin your life. Instead, let the Holy Spirit fill and control you.  (NLT - Tyndale House)
Phillips: Don't get your stimulus from wine (for there is always the danger of excessive drinking), but let the Spirit stimulate your souls. (
Phillips: Touchstone)
Wuest: And stop being intoxicated with wine, in which state of intoxication there is profligacy. But be constantly controlled by the Spirit,  (
Erdmans
Young's Literal:  and be not drunk with wine, in which is dissoluteness, but be filled in the Spirit,

AND DO NOT GET DRUNK WITH WINE: kai me methuskesthe (2PPPM) oino: (Genesis 9:21; 19:32-35; Deuteronomy 21:20; Psalms 69:12; Proverbs 20:1; 23:20,21,29-35; Isaiah 5:11-13,22; Matthew 24:49; Luke 12:45; 21:34; Romans 13:13; 1 Corinthians 5:11; 6:10; 1 Corinthians 11:21; Galatians 5:21; 1 Thessalonians 5:7)

And - It is sad that too often this great teaching is taken out of its context. The point is that the Greek connective "and" (kai) clearly links it with the preceding verses. The obvious implication is that being continually filled with the Spirit is intimately related to the will of God and also to making the most of one's time.

Respected evangelical Pastor Ray Pritchard wrote that

the filling of the Spirit is the most important doctrine of the spiritual life. It is foundational to everything else. There is nothing we need more. Here is my definition of the filling of the Spirit: It is that state in which the Holy Spirit is free to do all that He came into my life to do. In a sense being filled with the Spirit is an impossibility-at least as far as it depends on us. Only God's Spirit can fill us. We need two things-emptiness and openness. You can't fill a jar that's already full, and you can't fill a jar that is not open. There must be a sense of need-"Lord, I'm empty and I need to be filled by Your Spirit." There must be a willingness-"Lord, I'm open to You..." The filling of the Spirit is really as simple as that. As long as we are conscious of our need and as long as we are willing to yield to the Lord, we can be filled with the Lord all day long. This power is available to us all day long. (Ephesians 5:18: Filled with the Holy Spirit?)

The NLT although a paraphrase presents an accurate sense of the meaning of the original Greek...

Don't be drunk with wine, because that will ruin your life. Instead, let the Holy Spirit fill and control you.

Eugene Peterson writes...

"Don't drink too much wine. That cheapens your life. Drink the Spirit of God, huge draughts of him."

(Do not) Get drunk (3182) (methusko from methuo = drink to intoxication) means to get drunk or become intoxicated. Both wine and the Spirit do their work deep in the human psyche. They affect people below the level of consciousness, down at the foundations of personality. The Spirit is not merely with God's people but in them. The present imperative with a negative commands them to stop an action already in progress. (Forbidden as a habit and to stop it also if guilty)

Vincent writes that...

In the Septuagint the verb repeatedly occurs for watering (Ps. 65:9, 10), but always with the sense of drenching or soaking; of being drunken or surfeited with water. In Jer. 48 (Sept. 31) 26, it is found in the literal sense, to be drunken. The metaphorical use of the word has passed into common slang, as when a drunken man is said to be wetted or soaked (so Plato, above). The figurative use of the word in the Septuagint has a parallel in the use of potizo, to give to drink, to express the watering of ground. So Gen. 2:6, a mist watered the face of the earth, or gave it drink. Compare Gen. 13:10; Deut. 11:10. A curious use of the word occurs in Homer, where he is describing the stretching of a bull’s hide, which, in order to make it more elastic, is soaked (methuousan) with fat (“Iliad,” xvii., 390). (Vincent, M. R.  Word Studies in the New Testament 2:82)

There are 30 uses of methusko in the Septuagint (LXX) (Gen. 9:21; 43:34; Deut. 32:42; 1 Sam. 1:14; 2 Sam. 11:13; Ps. 23:5; 36:8; 65:9f; Prov. 4:17; 23:31; Cant. 5:1; Isa. 7:20; 34:5, 7; 49:26; 55:10; Jer. 25:27; 31:13, 25; 46:10; 48:26; 51:7, 39, 57; Lam. 3:15; 4:21; Hos. 14:7; Nah. 3:11; Hab. 2:15; Lk. 12:45; Jn. 2:10; Eph. 5:18; 1 Thess. 5:7; Rev. 17:2) and 5 in the NT...

Luke 12:45 "But if that slave says in his heart, 'My master will be a long time in coming,' and begins to beat the slaves, both men and women, and to eat and drink and get drunk;

John 2:10 and said to him, "Every man serves the good wine first, and when men have drunk freely, then that which is poorer; you have kept the good wine until now."

Ephesians 5:18 And do not get drunk with wine, for that is dissipation, but be filled with the Spirit,

1 Thessalonians 5:7 For those who sleep do their sleeping at night, and those who get drunk get drunk at night.

Revelation 17:2 with whom the kings of the earth committed acts of immorality, and those who dwell on the earth were made drunk with the wine of her immorality."

Wuest has an interesting comment on methusko writing that...

A curious use of the word occurs in Homer, where he is describing the stretching of a bull’s hide, which in order to make it more elastic, is soaked (methusko) with fat.” The word, therefore, refers to the condition of a person in which he is soaked with wine. (Wuest, K. S. Wuest's Word Studies from the Greek New Testament: Eerdmans

Wine (3631) (oinos) is the fermented drink common in the Ancient near east. The wine most commonly drunk in Paul’s day was either nonalcoholic or had very low alcohol content. Fermented juice was mixed with water (as much as 8 or 10 parts water to 1 part wine) to lessen its power to intoxicate, particularly when the weather was hot and much fluid was consumed. Because water was frequently contaminated, as in many third world countries, the slight alcohol content of common wine acted as a disinfectant and had certain other health benefits.

Dr. Martyn Lloyd-Jones wrote

Drink is not a stimulus, it is a depressant. It depresses first and foremost the highest centers of all in the brain. They are the very first to be influenced and affected by drink. They control everything that gives a man self-control, wisdom, understanding, discrimination, judgment, balance, the power to assess everything; in other words everything that makes a man behave at his very best and highest. The better a man’s control, the better man he is.… But drink is something which immediately gets rid of control; that indeed is the first thing it does.

FOR THAT IS DISSIPATION: en o estin (3SPAI) asotia:  (Matthew 23:25; 1 Peter 4:3,4)

For that is dissipation - for that is debauchery and it will ruin your life.

Dissipation (810) (riot, KJV) (asotia related to ásotos which in turn is derived from a = negative + sozo  = save which describes something devoid of saving quality) literally means that which cannot be saved. Strictly speaking asotia refers to the disposition of an ásotos or prodigal. It is the picture of having no hope of safety, then describing the act of one who has abandoned himself to such reckless behavior. Asotia conveys the idea of waste that is irretrievable.